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2025

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Modulation of Intestinal Microbiota Through Kefir-Based Beverages in a Murine Model of Acute Pancreatitis

Aguirre-Ramírez D, Garrido M, Sánchez L, Grasa L.

Molecular Nutrition & Food Research. 2025 Oct 29; doi: 10.1002/mnfr.70304
 

Differential protective effects of whole and skimmed whey on LPS-induced barrier dysfunction and inflammation in Caco-2/TC7 cells

Layunta E, García L, Gimeno S, Martínez J, Sánchez L, Grasa L.

Functional Foods in Health and Disease. 2025 Nov 17;15(11); doi: 10.31989/ffhd.v15i11.1774
 

Assessing the microbiome of a poultry burger processing line: A combined approach using culturing techniques and metabarcoding

Merino N, Espina L, Pagán E, Vlamakis H, Grasa L, Berdejo D, Pagán R, García-Gonzalo D.

LWT - Food Science and Technology. 2025 Feb 1;217:117392; doi: 10.1016/j.lwt.2025.117392
 

Gut microbiota alterations linked to classical scrapie in sheep

Hernaiz A, Grasa L, De Diego Abejón P, León Huertas C, Marín B, Badiola J.J, Bolea R, Zaragoza P, Martín-Burriel I.

Research in Veterinary Science. 2025 Nov;196:105916; doi: 10.1016/j.rvsc.2025.105916

 

Effects of kefirs made from whole milk or whey on the pancreas-intestine axis in a mouse model of acute pancreatitis

Aguirre-Ramírez D, Abás E, Gómez Á, Luján L, Pérez E, Sánchez L, Grasa L.

Food & Function. 2025;16:9628-9641; doi: 10.1039/D5FO02770E
 

Protective role of bovine lactoferrin in modulating the intestinal serotonergic system: Implications in intestinal inflammation

Buey B, Abad I, Bellés A, Castro M, Valero M.S, Arruebo M.P, Grasa L, Sánchez L, Plaza M.A, Mesonero J.E, Latorre E.

The Journal of Nutritional Biochemistry. 2025;146:110073; doi: 10.1016/j.jnutbio.2025.110073
 

Effect of the Consumption of Lean Red Meat from Beef (Pirenaica Breed) Versus Lean White Meat (Chicken) on the Gut Microbiota: A Randomized Cross‐Over Study in Healthy Young Adults

Rueda-De Torre I, Plaza-Diaz J, Miguel-Berges M.L, Gil A, Grasa L, Esteban L.M, Sabroso-Lasa S, Campo M.M, Santolaria P, Moreno L.A, Santaliestra-Pasías A.M.

Molecular Nutrition & Food Research. 2025 Nov;69(21):e70189; doi: 10.1002/mnfr.70189
 

Buttermilk and Whey as Functional Foods to Ameliorate Clindamycin-Induced Changes in Mouse Intestine: Modulation of Intestinal Motility and Toll-like Receptors Expression

Bellés A, Abad I, Buey B, Vergara C, Mesonero J.E, Sánchez L, Grasa L.

Journal of Medicinal Food. 2025 Feb;28(2):205-211; doi: 10.1089/jmf.2024.0155
 

Lactoferrin modulates oxidative stress and inflammatory cytokines in a murine model of dysbiosis induced by clindamycin

Abad I, Bellés A, Rodríguez-Largo A, Luján L, de Blas I, Graikini D, Grasa L, Sánchez L.

Biochemistry and Cell Biology. 2025 Jan 1;103:1-12; doi: 10.1139/bcb-2024-0087
 

 

2024

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Microbes and Parameters Influencing Dark Fermentation for Hydrogen Production

Gupta S, Fernandes A, Lopes A, Grasa L, Salafranca J.

Appl Sci. 2024 Nov 21; 14 (23). doi: 10.3390/app142310789.

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Buttermilk and Whey as Functional Foods to Ameliorate Clindamycin-Induced Changes in Mouse Intestine: Modulation of Intestinal Motility and Toll-like Receptors Expression

Bellés A, Abad I, Buey B, Vergara C, Mesonero J.E, Sánchez L, Grasa L.

J of Medicinal Food. 2024 Nov 7; doi: 10.1089/jmf.2024.0155.

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Antibacterial activity and antioxidant capacity of dairy kefir beverages

Aguirre-Ramírez D, Abad I, Pinilla E, Pérez M.D, Grasa L, Sánchez L. 

International Journal of Dairy Technology. 2024 Oct 27; https://doi.org/10.1111/1471-0307.13153

 

Lactoferrin modulates oxidative stress and inflammatory cytokines in a murine model of dysbiosis induced by clindamycin

Abad I, Bellés A, Rodríguez-Largo A, Luján L, de Blas I, Graikini D, Grasa L, Sánchez L.

Biochem Cell Biol. 2024 Oct 8; doi: 10.1139/bcb-2024-0087

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Photo-Fermentative Bacteria Used for Hydrogen Production

Gupta S, Fernandes A, Lopes A, Grasa L, Salafranca J. 

Appl Sci. 2024 Jan 31; 14 (3). doi: 10.3390/app14031191.

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2023

 

Whey and Buttermilk-Based Formulas Modulate Gut Microbiota in Mice with Antibiotic-Induced Dysbiosis

Bellés A, Abad I,  Sánchez L, Grasa L. 

Mol Nutr Food Res. 2023 Oct; 67 (20). doi: 10.1002/mnfr.202300248 

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Effect of in vitro gastrointestinal digestion on the antibacterial activity of bioactive dairy formulas supplemented with lactoferrin against Cronobacter sakazakii

Abad I, Serrano L, Graikini D, Pérez MD, Grasa L, Sánchez L.

Biometals. 2023 Nov 06; 36: 667-681. doi: 10.1007/s10534-022-00459-5

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The Role of Lactoferrin in Intestinal Health

Conesa C, Bellés A, Grasa L, Sánchez L.

Pharmaceutics. 2023 Jul 13; 15 (6). doi: 10.3390/pharmaceutics15061569

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Dairy By-Products and Lactoferrin Exert Antioxidant and Antigenotoxic Activity on Intestinal and Hepatic Cells

Abad I, Vignard J, Bouchenot C, Graikini D, Grasa L, Pérez MD, Mirey G,  Sánchez L.

Foods. 2023 Jun 15; 12 (10). doi: 10.3390/foods12102073

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Gut Microbiota-Derived Short-Chain Fatty Acids: Novel Regulators of Intestinal Serotonin Transporter

Buey B, Forcen A, Grasa L, Layunta E, Mesonero JE, Latorre E.

Life. 2023, April 26; 13 (5). doi: 10.3390/life13051085

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Effect of a Ketogenic Medium Chain Triglyceride-Enriched Diet on the Fecal Microbiota in Canine Idiopathic Epilepsy: A Pilot Study

García-Belenguer S, Grasa L, Palacio J, Moral J,  Rosado B.

Vet Sci. 2023, May 22; 10(4). doi: 10.3390/vetsci10040245

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2022

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Editorial: Molecular Mechanisms of Chronic Intestinal Diseases in Response to Microbiota
Grasa L.

Cells. 2022, Dec 29; 11 (23). doi:10.3390/cells11233722

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Antitumor effects of lactate transport inhibition on esophageal adenocarcinoma cells.

Grasa L, Chueca E, Arechavaleta S, García-González MA, Sáenz MÁ, Valero A, Hördnler C, Lanas Á, Piazuelo E.

J Physiol Biochem. 2022 Nov 7; 79 (1): 147-161. doi: 10.1007/s13105-022-00931-3. 

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Editorial: Emerging talents in Frontiers in pharmacology: Gastrointestinal and hepatic pharmacology 2022.

Grasa L, Brzozowski T, Seelaender M.

Front Pharmacol. 2022 Oct 21; 13. doi: 10.3389/fphar.2022.1055030.

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Protective effect of bovine lactoferrin against Cronobacter sakazakii in human intestinal Caco-2/TC7 cells.
Abad A, Sangüesa A, Ubieto M, Carramiñana JJ, Perez MD, Buey B, Mesonero JE, Grasa L, Sánchez L.

International Dairy J. 2022 Oct;133. doi: 10.1016/j.idairyj.2022.105428

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Intestinal serotonergic system is modulated by Toll-like receptor 9.

Layunta E, Latorre E, Grasa L, Arruebo MP, Buey B, Alcalde AI, Mesonero JE.

J Physiol Biochem. 2022 Aug; 78(3):689-701. doi: 10.1007/s13105-022-00897-2. ​

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TLR2 and TLR4 Modulate Mouse Ileal Motility by the Interaction with Muscarinic and Nicotinic Receptors.

Layunta E, Forcén R, Grasa L.

Cells. 2022 May 30; 11(11). doi: 10.3390/cells11111791.

 

Lactoferrin modulates gut microbiota and Toll-like receptors (TLRs) in mice with dysbiosis induced by antibiotics.

Bellés A, Aguirre-Ramírez D, Abad I, Parras-Moltó M, Sánchez L, Grasa L.

Food Funct. 2022 April 18; 13(10):5854-5869. doi: 10.1039/d2fo00287f.

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Intrinsic and selective activity of functionalized carbon nanotube/nanocellulose platforms against colon cancer cells.

González-Domínguez JM, Grasa L, Frontiñán-Rubio J, Abás E, Domínguez-Alfaro A, Mesonero JE, Criado A, Ansón-Casaos A.

Colloids Surf B Biointerfaces. 2022 Apr; 212. doi:10.1016/j.colsurfb.2022.112363.

 

The Significant Influence of a Second Metal on the Antiproliferative Properties of the Complex [Ru(η6 -C10 H14 )(Cl2 )(dmoPTA)].

Kordestani N, Abas E, Grasa L, Alguacil A, Scalambra F, Romerosa A.

Chemistry. 2022, Jan 13; 28(3). doi: 10.1002/chem.202103048. 

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2021

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Selective Anticancer and Antimicrobial Metallodrugs Based on Gold(III) Dithiocarbamate Complexes.

Abás E, Aguirre-Ramírez D, Laguna M, Grasa L.

Biomedicines. 2021 Nov 26; 9(12). doi: 10.3390/biomedicines9121775.

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Gut Microbiota in Canine Idiopathic Epilepsy: Effects of Disease and Treatment.

García-Belenguer S, Grasa L, Valero O, Palacio J, Luño B, Rosado B.

Animals. 2021 Oct 31, 11(11). doi:10.3390/ani11113121

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Effects of Dietary Supplementation with Protected Sodium Butyrate on Gut Microbiota in Growing-Finishing Pigs.

Bernad-Roche M, Bellés A, Grasa L, Casanova-Higes A, Mainar-Jaime RC.

Animals. 2021, Jul 19, 11(7) .doi:10.3390/ani11072137

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Selective cytotoxicity of cyclometalated gold(III) complexes on Caco-2 cells is mediated by G2/M cell cycle arrest.

Abás E, Bellés A, Rodríguez-Diéguez A, Laguna M, Grasa L.

Metallomics. 2021 Jun 10; 13(7). doi: 10.1093/mtomcs/mfab034. 

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Comparative effect of bovine buttermilk, whey, and lactoferrin on the innate immunity receptors and oxidative status of intestinal epithelial cells.

Buey B, Bellés A, Latorre E, Abad I, Pérez MD, Grasa L, Mesonero JE, Sánchez L.

Biochem Cell Biol. 2021 Feb; 99(1):54-60. doi: 10.1139/bcb-2020-0121. 

 

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